The World Health Organization (WHO) published global guidance on the recommended daily iron supplementation in infants and children as an intervention for preventing iron deficiency and anemia. It recommends daily iron supplementation for three consecutive months in a year in areas where anemia prevalence is 40 percent or higher, for children 6-23 months (10-12.5 mg), 24-59 months (30 mg), and children over 60 months (30-60mg). These regimens are to be carried out in conjunction with prevention, diagnosis, and treatment of malaria. This guideline summarizes those recommendations and supporting evidence, as well as other considerations and research priorities. It is intended for a wide audience, including policymakers, technical staff at government institutions, and program implementers.